The tasks of the Neuromics project are arranged into ‘workpackages’ each with a particular focus and set of objectives. Each workpackage has a leading organisation which is responsible for its overall progress and reporting. More details about each can be found below….
Workpackage 1 led by Thomas Klockgether
Deep phenotype analysis in pre-symptomatic and symptomatic NDD/NMD patients
Workpackage 2 led by Brunhilde Wirth
Identification of novel disease genes in NDD/NMD patients
Workpackage 3 led by Sarah Tabrizi
Identification of modifying factors in cohorts enriched by deep phenotyping
Workpackage 4 led by Alexis Brice
Identification of hypothesis-driven biomarkers for disease progression
Workpackage 5 led by Olaf Riess
Development and implementation of disease group overlapping NGS-based diagnostic panels
Workpackage 6 led by Nicolas Lévy
Diagnostic read outs for predicting disease modification
Workpackage 7 led by Alexandra Durr
Omics-based biomarkers for progression and therapy monitoring related to disease pathways
Workpackage 8 led by Henk Jan Joosten
Bioinformatic tools for diagnostic prediction
Workpackage 9 led by Annemieke Aartsma-Rus
Omics-assisted therapy development
Workpackage 10 led by Elena Cattaneo
Elucidation of pathogenesis and monitoring of treatment
Workpackage 11 led by David Rubinsztein
Modifier gene identification, prioritization and study
Workpackage 12 led by Volker Straub
Impact and communication
Workpackage 13 led by Volker Straub
Research infrastructure
Workpackage 14 led by Holm Graessner
Project Management
